Genotypic Characterization of Clarithromycin-Resistant and -Susceptible Helicobacter pylori Strains from the Same Patient Demonstrates Existence of Two Unrelated Isolates
نویسندگان
چکیده
منابع مشابه
Characterization of rifampicin-resistant clinical Helicobacter pylori isolates from Germany.
OBJECTIVES The aim of this study was to assess the rate of rifampicin resistance in Helicobacter pylori isolated from patients in Germany, to detect rifampicin resistance-associated mutations and to identify non-resistance-associated genetic variants in the rpoB gene. METHODS Susceptibility to rifampicin in a total of 1585 clinical isolates obtained between January 2003 and July 2006 was test...
متن کاملCharacterization of clarithromycin resistance in isolates of Helicobacter pylori from the UAE.
BACKGROUND Clarithromycin therapy is effective in eradicating Helicobacter pylori. However, the resistance of H. pylori to clarithromycin is increasingly reported. The present study aimed to characterize the types of mutations present in the 23S rRNA genes of isolates of clarithromycin-resistant H. pylori from the UAE. METHODS Clarithromycin susceptibility of H. pylori isolates (n = 26) was d...
متن کاملCharacterization of 23S rRNA gene mutation in primary and secondary clarithromycin-resistant Helicobacter pylori strains from East China.
BACKGROUND/AIMS Clarithromycin is an effective antibiotic for treating Helicobacter pylori; however, the development clarithromycin- resistance by multiple strains prevents the eradication of Helicobacter pylori. We aimed to characterize mutations in the 23S rRNA gene of primary clarithromycin-sensitive, primary clarithromycin-resistant and secondary clarithromycin-resistant Helicobacter pylori...
متن کاملHelicobacter pylori Eradication Rate in Clarithromycin-resistant Strains By Pantoprazole - Amoxicillin - Clarithromycin Regimen
Background: Clarithromycin resistance is an increasing problem in this part of the world and it potentially has an impact on the eradication rate of first line triple therapy (proton pump inhibitorAmoxicillinClarithromycin) for Helicobacter pylori (H. pylori) infection. Objective: This study was designed to determine the effect of clarithromycin resistance on the efficacy of Pantoprazole-Amoxic...
متن کاملIntrafamilial spread of the same clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis.
Clarithromycin-resistant Helicobacter pylori (CRHP) is increasing worldwide, especially in children. We report a family case in which both the mother and child were infected with CRHP. DNA analysis revealed that all of the mother's and daughter's isolates were indistinguishable, suggesting that the same CRHP strain spread between the family members. The spread of CRHP within families may be inc...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1998
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.36.9.2730-2731.1998